Anti-proliferative and anti-migratory properties of coffee diterpenes kahweol acetate and cafestol in human renal cancer cells

Despite improvements in systemic therapy options for renal cancer, it remains one of the most drug-resistant malignancies. Interestingly, reports have shown that kahweol and cafestol, natural diterpenes extracted from coffee beans, exhibit anti-cancer activity. However, the multiple potential pharma...

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Publicado en:Sci Rep
Autores principales: Makino, Tomoyuki, Izumi, Kouji, Hiratsuka, Kaoru, Kano, Hiroshi, Shimada, Takashi, Nakano, Taito, Kadomoto, Suguru, Naito, Renato, Iwamoto, Hiroaki, Yaegashi, Hiroshi, Shigehara, Kazuyoshi, Kadono, Yoshifumi, Nakata, Hiroki, Saito, Yohei, Nakagawa-Goto, Kyoko, Sakai, Norihiko, Iwata, Yasunori, Wada, Takashi, Mizokami, Atsushi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804192/
https://ncbi.nlm.nih.gov/pubmed/33436830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80302-4
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