Uraemic toxins impair skeletal muscle regeneration by inhibiting myoblast proliferation, reducing myogenic differentiation, and promoting muscular fibrosis

Uraemic toxins increase in serum parallel to a decline in the glomerular filtration rate and the development of sarcopenia in patients with chronic kidney disease (CKD). This study analyses the role of uraemic toxins in sarcopenia at different stages of CKD, evaluating changes in the muscular regene...

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Vydáno v:Sci Rep
Hlavní autoři: Alcalde-Estévez, Elena, Sosa, Patricia, Asenjo-Bueno, Ana, Plaza, Patricia, Olmos, Gemma, Naves-Díaz, Manuel, Rodríguez-Puyol, Diego, López-Ongil, Susana, Ruiz-Torres, María P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7804102/
https://ncbi.nlm.nih.gov/pubmed/33436654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79186-1
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