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CYP3A4 mediated pharmacokinetics drug interaction potential of Maha-Yogaraj Gugglu and E, Z guggulsterone

Maha yogaraja guggulu (MYG) is a classical herbomineral polyherbal formulation being widely used since centuries. The aim of this study was to investigate the effect of MYG formulation and its major constituents E & Z guggulsterone on CYP3A4 mediated metabolism. In vitro inhibition of MYG and Gu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sabarathinam, Sarvesh, Rajappan Chandra, Satish Kumar, Thangavel Mahalingam, Vijayakumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803744/
https://ncbi.nlm.nih.gov/pubmed/33436877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80595-5
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