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Silencing hTERT attenuates cancer stem cell-like characteristics and radioresistance in the radioresistant nasopharyngeal carcinoma cell line CNE-2R

Objective: This study aimed to explore the effect of silencing hTERT on the CSC-like characteristics and radioresistance of CNE-2R cells. Results: Silencing hTERT suppressed CNE-2R cell proliferation and increased the cell apoptosis rate and radiosensitivity in vitro. Moreover, it could also inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Chen, Kaihua, Li, Ling, Qu, Song, Pan, Xinbin, Sun, Yongchu, Wan, Fangzhu, Yu, Binbin, Zhou, Lei, Zhu, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803545/
https://ncbi.nlm.nih.gov/pubmed/33234740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104167
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