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miRNA-122-5p stimulates the proliferation and DNA synthesis and inhibits the early apoptosis of human spermatogonial stem cells by targeting CBL and competing with lncRNA CASC7

Epigenetic regulators of human spermatogonia stem cells (SSCs) remain largely unknown. We found that miRNA-122-5p was upregulated in human spermatogonia from obstructive azoospermia (OA) patients compared with non-obstructive azoospermia (NOA). MiRNA-122-5p stimulated the proliferation and DNA synth...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Zhou, Fan, Chen, Wei, Cui, Yinghong, Liu, Bang, Yuan, Qingqing, Li, Zheng, He, Zuping
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803487/
https://ncbi.nlm.nih.gov/pubmed/33231565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.104158
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