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UNC-45A breaks the microtubule lattice independently of its effects on non-muscle myosin II

In invertebrates, UNC-45 regulates myosin stability and functions. Vertebrates have two distinct isoforms of the protein: UNC-45B, expressed in muscle cells only, and UNC-45A, expressed in all cells and implicated in regulating both non-muscle myosin II (NMII)- and microtubule (MT)-associated functi...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Habicht, Juri, Mooneyham, Ashley, Hoshino, Asumi, Shetty, Mihir, Zhang, Xiaonan, Emmings, Edith, Yang, Qing, Coombes, Courtney, Gardner, Melissa K., Bazzaro, Martina
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803465/
https://ncbi.nlm.nih.gov/pubmed/33262310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.248815
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