Reversal of the Pathophysiological Responses to Gram-Negative Sepsis by Megadose Vitamin C

Oxidative stress appears to initiate organ failure in sepsis, justifying treatment with antioxidants such as vitamin C at megadoses. We have therefore investigated the safety and efficacy of megadose sodium ascorbate in sepsis. DESIGN: Interventional study. SETTING: Research Institute. SUBJECTS: Adu...

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Dades bibliogràfiques
Publicat a:Crit Care Med
Autors principals: Lankadeva, Yugeesh R., Peiris, Rachel M., Okazaki, Nobuki, Birchall, Ian E., Trask-Marino, Anton, Dornom, Anthony, Vale, Tom A. M., Evans, Roger G., Yanase, Fumitaka, Bellomo, Rinaldo, May, Clive N.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2020
Matèries:
Online Laboratory Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7803449/
https://ncbi.nlm.nih.gov/pubmed/33239507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CCM.0000000000004770
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