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A Novel Long-Term Graves' Disease Animal Model Confirmed by Functional Thyrotropin Receptor Antibodies

INTRODUCTION: A novel long-term murine model for Graves' disease (GD) using repeated, long-term immunizations with recombinant adenovirus expressing the extracellular A-subunit of the human thyrotropin receptor (Ad-TSHR) was applied to evaluate the functional anti-TSHR-antibody (TSHR-Ab) profil...

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Vydáno v:Eur Thyroid J
Hlavní autoři: Diana, Tanja, Holthoff, Hans-Peter, Fassbender, Julia, Wüster, Christian, Kanitz, Michael, Kahaly, George J., Ungerer, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: S. Karger AG 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802450/
https://ncbi.nlm.nih.gov/pubmed/33511085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000508790
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