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Morphological study of embryonic Chd8(+/−) mouse brains using light-sheet microscopy

OBJECTIVE: Autism spectrum disorder (ASD) encompasses a group of neurodevelopmental conditions that remain poorly understood due to their genetic complexity. CHD8 is a risk allele strongly associated with ASD, and heterozygous Chd8 loss-of-function mice have been reported to exhibit macrocephaly in...

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Bibliografiske detaljer
Udgivet i:BMC Res Notes
Main Authors: Gómez, Harold F., Hodel, Leonie, Michos, Odyssé, Iber, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7802325/
https://ncbi.nlm.nih.gov/pubmed/33436073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-020-05436-0
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