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Preoperative detection of KRAS mutated circulating tumor DNA is an independent risk factor for recurrence in colorectal cancer

Preoperative ctDNA status in relation to recurrence in cases of CRC remains unclear. We examined preoperative ctDNA detection by targeting KRAS gene mutations as a predictive marker for recurrence after CRC surgery. We measured the preoperative KRAS mutated ctDNA status and analyzed the correlation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakamura, Yuki, Yokoyama, Shozo, Matsuda, Kenji, Tamura, Koichi, Mitani, Yasuyuki, Iwamoto, Hiromitsu, Mizumoto, Yuki, Murakami, Daisuke, Kitahata, Yuji, Yamaue, Hiroki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801374/
https://ncbi.nlm.nih.gov/pubmed/33432066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79909-4
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