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Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure–response analysis
PURPOSE: This study assessed the effect of lurbinectedin, a highly selective inhibitor of oncogenic transcription, on the change from baseline in Fridericia’s corrected QT interval (∆QTcF) and electrocardiography (ECG) morphological patterns, and lurbinectedin concentration–∆QTcF (C-∆QTcF) relations...
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| Publicado no: | Cancer Chemother Pharmacol |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7801313/ https://ncbi.nlm.nih.gov/pubmed/33108504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04153-6 |
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