Effect of lurbinectedin on the QTc interval in patients with advanced solid tumors: an exposure–response analysis

PURPOSE: This study assessed the effect of lurbinectedin, a highly selective inhibitor of oncogenic transcription, on the change from baseline in Fridericia’s corrected QT interval (∆QTcF) and electrocardiography (ECG) morphological patterns, and lurbinectedin concentration–∆QTcF (C-∆QTcF) relations...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Fudio, Salvador, Tabernero, Josep, Subbiah, Vivek, Chawla, Sant P., Moreno, Victor, Longo, Federico, Lopez, Rafael, Anton, Antonio, Trigo, Jose Manuel, Shapiro, Geoffrey, Jeong, Woondong, Villalobos, Victor Manuel, Lubomirov, Rubin, Fernandez-Teruel, Carlos, Alfaro, Vicente, Boni, Valentina
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7801313/
https://ncbi.nlm.nih.gov/pubmed/33108504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-020-04153-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados