Hippocampal low-frequency stimulation prevents seizure generation in a mouse model of mesial temporal lobe epilepsy

Mesial temporal lobe epilepsy (MTLE) is the most common form of focal, pharmacoresistant epilepsy in adults and is often associated with hippocampal sclerosis. Here, we established the efficacy of optogenetic and electrical low-frequency stimulation (LFS) in interfering with seizure generation in a...

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Publicat a:eLife
Autors principals: Paschen, Enya, Elgueta, Claudio, Heining, Katharina, Vieira, Diego M, Kleis, Piret, Orcinha, Catarina, Häussler, Ute, Bartos, Marlene, Egert, Ulrich, Janz, Philipp, Haas, Carola A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2020
Matèries:
Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7800381/
https://ncbi.nlm.nih.gov/pubmed/33349333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54518
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