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A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation

Enteric glial cells (EGC) modulate motility, maintain gut homeostasis, and contribute to neuroinflammation in intestinal diseases and motility disorders. Damage induces a reactive glial phenotype known as “gliosis”, but the molecular identity of the inducing mechanism and triggers of “enteric gliosi...

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Publicado en:EMBO Mol Med
Main Authors: Schneider, Reiner, Leven, Patrick, Glowka, Tim, Kuzmanov, Ivan, Lysson, Mariola, Schneiker, Bianca, Miesen, Anna, Baqi, Younis, Spanier, Claudia, Grants, Iveta, Mazzotta, Elvio, Villalobos‐Hernandez, Egina, Kalff, Jörg C, Müller, Christa E, Christofi, Fedias L, Wehner, Sven
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799361/
https://ncbi.nlm.nih.gov/pubmed/33332729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012724
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