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Inferring microenvironmental regulation of gene expression from single-cell RNA sequencing data using scMLnet with an application to COVID-19

Inferring how gene expression in a cell is influenced by cellular microenvironment is of great importance yet challenging. In this study, we present a single-cell RNA-sequencing data based multilayer network method (scMLnet) that models not only functional intercellular communications but also intra...

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Detalhes bibliográficos
Publicado no:Brief Bioinform
Main Authors: Cheng, Jinyu, Zhang, Ji, Wu, Zhongdao, Sun, Xiaoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7799217/
https://ncbi.nlm.nih.gov/pubmed/33341869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bib/bbaa327
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