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Prevalence of class I–III BRAF mutations among 114,662 cancer patients in a large genomic database

BRAF mutations are relatively common in many cancers, particularly melanoma, colorectal cancer, and thyroid cancer and to a lesser extent in lung cancer. These mutations can be targeted by BRAF and MEK inhibitors, which exhibit good clinical activity. There are conflicting reports of the various rel...

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Bibliografiske detaljer
Udgivet i:Exp Biol Med (Maywood)
Main Authors: Owsley, Jeff, Stein, Matthew K, Porter, Jason, In, Gino K, Salem, Mohamed, O’Day, Steven, Elliott, Andrew, Poorman, Kelsey, Gibney, Geoffrey, VanderWalde, Ari
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797994/
https://ncbi.nlm.nih.gov/pubmed/33019809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370220959657
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