NEK9, a novel effector of IL-6/STAT3, regulates metastasis of gastric cancer by targeting ARHGEF2 phosphorylation

Rationale: Inflammatory stimuli from the tumor microenvironment play important roles in cancer progression. However, the mechanism of promotion of cancer metastasis by inflammation in gastric cancer (GC) is poorly understood. Methods: The roles of NEK9 were validated via loss-of-function and gain-of...

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Publicat a:Theranostics
Autors principals: Lu, Guofang, Tian, Siyuan, Sun, Yi, Dong, Jiaqiang, Wang, Na, Zeng, Jiaoxia, Nie, Yongzhan, Wu, Kaichun, Han, Ying, Feng, Bin, Shang, Yulong
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797683/
https://ncbi.nlm.nih.gov/pubmed/33500736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.53169
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