CYP1A2 suppresses hepatocellular carcinoma through antagonizing HGF/MET signaling

Rationale: Hyperactivation of HGF/MET signaling pathway is a critical driver in liver tumorigenesis. Cytochrome P450 1A2 (CYP1A2) was significantly down-regulated in hepatocellular carcinoma (HCC). However, little is explored about its tumor suppressive role in HCC. In this study, we examined the fu...

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Bibliographic Details
Published in:Theranostics
Main Authors: Yu, Jianqing, Xia, Xianfeng, Dong, Yujuan, Gong, Zhongqin, Li, Gang, Chen, George Gong, Lai, Paul Bo San
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2021
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797680/
https://ncbi.nlm.nih.gov/pubmed/33500715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.49368
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