Inhibition of miR-331-3p and miR-9-5p ameliorates Alzheimer's disease by enhancing autophagy

Alzheimer's disease (AD) is currently ranked as the third leading cause of death for eldly people, just behind heart disease and cancer. Autophagy is declined with aging. Our study determined the biphasic changes of miR-331-3p and miR-9-5p associated with AD progression in APPswe/PS1dE9 mouse m...

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Publicat a:Theranostics
Autors principals: Chen, Meng-Lu, Hong, Chun-Gu, Yue, Tao, Li, Hong-Ming, Duan, Ran, Hu, Wen-Bao, Cao, Jia, Wang, Zhen-Xing, Chen, Chun-Yuan, Hu, Xiong-Ke, Wu, Ben, Liu, Hao-Ming, Tan, Yi-Juan, Liu, Jiang-Hua, Luo, Zhong-Wei, Zhang, Yan, Rao, Shan-Shan, Luo, Ming-Jie, Yin, Hao, Wang, Yi-Yi, Xia, Kun, Tang, Si-Yuan, Xie, Hui, Liu, Zheng-Zhao
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797673/
https://ncbi.nlm.nih.gov/pubmed/33500732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47408
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