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Trastuzumab deruxtecan for the treatment of patients with HER2-positive gastric cancer

Trastuzumab deruxtecan (T-DXd) is a novel anti-human epidermal growth factor receptor 2 (HER2) antibody–drug conjugate composed of a monoclonal anti-HER2 antibody and a topoisomerase I inhibitor, DX-8951 derivative (an exatecan derivative). T-DXd showed potential anti-tumor activities in HER2-positi...

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Bibliografiske detaljer
Udgivet i:Ther Adv Med Oncol
Main Authors: Kotani, Daisuke, Shitara, Kohei
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797586/
https://ncbi.nlm.nih.gov/pubmed/33473250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920986518
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