Allyl isothiocyanate (AITC) activates nonselective cation currents in human cardiac fibroblasts: possible involvement of TRPA1

The effects of allyl isothiocyanate (AITC), transient receptor potential ankyrin 1 (TRPA1) agonist, on cultured human cardiac fibroblasts were examined by measuring intracellular Ca(2+) concentration [Ca(2+)](i) and whole-cell voltage clamp techniques. AITC (200 μM) increased Ca(2+) entry in the pre...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Oguri, Gaku, Nakajima, Toshiaki, Kikuchi, Hironobu, Obi, Shotaro, Nakamura, Fumitaka, Komuro, Issei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797518/
https://ncbi.nlm.nih.gov/pubmed/33458442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05816
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