Flow cytometry detection of cell type-specific expression of programmed death receptor ligand-1 (PD-L1) in colorectal cancer specimens

AIM: PD-1/PD-L1 blockade therapy is now widely used for the treatment of advanced malignancies. Although PD-L1 is known to be expressed by various host cells as well as tumor cells, the role of PD-L1 on non-malignant cells and its clinical significance is unknown. We evaluated cell type-specific exp...

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Vydáno v:Heliyon
Hlavní autoři: Saito, Akira, Tojo, Mineyuki, Kumagai, Yuko, Ohzawa, Hideyuki, Yamaguchi, Hironori, Miyato, Hideyo, Sadatomo, Ai, Naoi, Daishi, Ota, Gaku, Koinuma, Koji, Horie, Hisanaga, Lefor, Alan Kawarai, Sata, Naohiro, Kitayama, Joji
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797507/
https://ncbi.nlm.nih.gov/pubmed/33458446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2020.e05880
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