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Protease inhibitor GC376 for COVID-19: Lessons learned from feline infectious peritonitis

The main protease (M(pro)) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important therapeutic target as it plays a major role in the processing and maturation of the viral polyprotein. GC376 is a pre-clinical dipeptide-based protease inhibitor that has been previously used f...

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Bibliografiske detaljer
Udgivet i:Ann Med Surg (Lond)
Main Authors: Sharun, Khan, Tiwari, Ruchi, Dhama, Kuldeep
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797473/
https://ncbi.nlm.nih.gov/pubmed/33456770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.amsu.2020.12.030
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