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ROS-mediated hypomethylation of PRDX5 promotes STAT3 binding and activates the Nrf2 signaling pathway in NSCLC
Deoxyribonucleic acid (DNA) epigenetic modification has been linked to specific sequences of CpG islands and plays roles in the progression of lung cancer. In this study, it was found that peroxiredoxin-5 (PRDX5) was highly expressed in non-small cell lung cancer (NSCLC) tissues; however, its specif...
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| Veröffentlicht in: | Int J Mol Med |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
D.A. Spandidos
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7797423/ https://ncbi.nlm.nih.gov/pubmed/33416106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2020.4819 |
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