Inhibition of N-type calcium channels in cardiac sympathetic neurons attenuates ventricular arrhythmogenesis in heart failure

AIMS: Cardiac sympathetic overactivation is an important trigger of ventricular arrhythmias in patients with chronic heart failure (CHF). Our previous study demonstrated that N-type calcium (Cav2.2) currents in cardiac sympathetic post-ganglionic (CSP) neurons were increased in CHF. This study inves...

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Publicado en:Cardiovasc Res
Autores principales: Zhang, Dongze, Tu, Huiyin, Wang, Chaojun, Cao, Liang, Hu, Wenfeng, Hackfort, Bryan T, Muelleman, Robert L, Wadman, Michael C, Li, Yu-Long
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797209/
https://ncbi.nlm.nih.gov/pubmed/31995173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvaa018
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