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Multi-conformation Monte Carlo: a Method for Introducing Flexibility in Efficient Simulations of Many-protein Systems

We present a novel multi-conformation Monte Carlo simulation method that enables the modeling of protein-protein interactions and aggregation in crowded protein solutions. This approach is relevant to a molecular-scale description of realistic biological environments, including the cytoplasm and the...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Prytkova, Vera, Heyden, Matthias, Khago, Domarin, Freites, J. Alfredo, Butts, Carter T., Martin, Rachel W., Tobias, Douglas J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797190/
https://ncbi.nlm.nih.gov/pubmed/27063730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b00827
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