e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks

Understanding the functional impact of cancer somatic mutations represents a critical knowledge gap for implementing precision oncology. It has been increasingly appreciated that the interaction profile mediated by a genomic mutation provides a fundamental link between genotype and phenotype. Howeve...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Li, Yongsheng, Burgman, Brandon, Khatri, Ishaani S, Pentaparthi, Sairahul R, Su, Zhe, McGrail, Daniel J, Li, Yang, Wu, Erxi, Eckhardt, S Gail, Sahni, Nidhi, Yi, S Stephen
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
Fag:
Methods Online
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797045/
https://ncbi.nlm.nih.gov/pubmed/33211847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1015
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