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Mechanism of Lamellar Body Formation by Lung Surfactant Protein B

Breathing depends on pulmonary surfactant, a mixture of phospholipids and proteins, secreted by alveolar type II cells. Surfactant requires lamellar bodies (LB), organelles containing densely packed concentric membrane layers, for storage and secretion. LB biogenesis remains mysterious, but requires...

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Publicado en:Mol Cell
Autores principales: Sever, Navdar, Miličić, Goran, Bodnar, Nicholas O., Wu, Xudong, Rapoport, Tom A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7797001/
https://ncbi.nlm.nih.gov/pubmed/33242393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.10.042
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