Negative stain electron microscopy reveals dramatic structural rearrangements in Ni-Fe-S dependent carbon monoxide dehydrogenase/acetyl-CoA synthase

The nickel-iron-sulfur-containing A-cluster of acetyl-CoA synthase (ACS) assembles acetyl-CoA from carbon monoxide (CO), a methyl group (CH(3)(+)), and coenzyme A (CoA). To accomplish this feat, ACS must bind CoA and interact with two other proteins that contribute the CO and CH(3)(+), respectively:...

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Vydáno v:Structure
Hlavní autoři: Cohen, Steven E., Brignole, Edward J., Wittenborn, Elizabeth C., Can, Mehmet, Thompson, Samuel, Ragsdale, Stephen W., Drennan, Catherine L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796957/
https://ncbi.nlm.nih.gov/pubmed/32937101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.08.011
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