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Integration of human cell lines gene expression and chemical properties of drugs for Drug Induced Liver Injury prediction

MOTIVATION: Drug-induced liver injury (DILI) is one of the primary problems in drug development. Early prediction of DILI can bring a significant reduction in the cost of clinical trials. In this work we examined whether occurrence of DILI can be predicted using gene expression profile in cancer cel...

詳細記述

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書誌詳細
出版年:Biol Direct
主要な著者: Lesiński, Wojciech, Mnich, Krzysztof, Golińska, Agnieszka Kitlas, Rudnicki, Witold R.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796564/
https://ncbi.nlm.nih.gov/pubmed/33422118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-020-00286-z
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