Tryptophan and Kynurenine Enhances the Stemness and Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stromal Cells In Vitro and In Vivo

Aging tissues present a progressive decline in homeostasis and regenerative capacities, which has been associated with degenerative changes in tissue-specific stem cells and stem cell niches. We hypothesized that amino acids could regulate the stem cell phenotype and differentiation ability of human...

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Detalhes bibliográficos
Publicado no:Materials (Basel)
Main Authors: Pham, Hai Thanh, Ono, Mitsuaki, Hara, Emilio Satoshi, Nguyen, Ha Thi Thu, Dang, Anh Tuan, Do, Hang Thuy, Komori, Taishi, Tosa, Ikue, Hazehara-Kunitomo, Yuri, Yoshioka, Yuya, Oida, Yasutaka, Akiyama, Kentaro, Kuboki, Takuo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796421/
https://ncbi.nlm.nih.gov/pubmed/33406724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ma14010208
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