Molecular Changes in Retinoblastoma beyond RB1: Findings from Next-Generation Sequencing

SIMPLE SUMMARY: The gene causing retinoblastoma was the first tumor suppressor cloned (1986) and because retinoblastoma is the classic example of autosomal dominant inheritance, there has been little research on non-RB1 alterations in tumors and the impact these alterations have on growth patterns i...

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Gepubliceerd in:Cancers (Basel)
Hoofdauteurs: Francis, Jasmine H., Richards, Allison L., Mandelker, Diana L., Berger, Michael F., Walsh, Michael F., Dunkel, Ira J., Donoghue, Mark T. A., Abramson, David H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796332/
https://ncbi.nlm.nih.gov/pubmed/33466343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13010149
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