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Synthetic Studies on the Incorporation of N-Acetylallosamine in Hyaluronic Acid-Inspired Thiodisaccharides

Two approaches for the synthesis of the thiodisaccharide β-S-GlcA(1→3)β-S-AllNAc are described here. The target disaccharide was a C-3 epimer and thio-analogue of the hyaluronic acid repetitive unit, tuned with a thiopropargyl anomeric group for further click conjugation. Thus, we analysed and teste...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Cristófalo, Alejandro E., Uhrig, María Laura
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796257/
https://ncbi.nlm.nih.gov/pubmed/33401465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26010180
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