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Specific Targeting of PEGylated Liposomal Doxorubicin (Doxil(®)) to Tumour Cells Using a Novel TIMP3 Peptide

Doxorubicin is a cytotoxic anthracycline derivative that has been used as a chemotherapeutic in many different forms of human cancer with some success. However, doxorubicin treatment has several side-effects, the most serious of which is cardiomyopathy, that can be fatal. Doxorubicin encapsulation i...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Aldughaim, Mohammed S., Muthana, Munitta, Alsaffar, Fatimah, Barker, Michael D.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795762/
https://ncbi.nlm.nih.gov/pubmed/33379361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules26010100
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