Newly Developed Recombinant Antithrombin Protects the Endothelial Glycocalyx in an Endotoxin-Induced Rat Model of Sepsis

(1) Background: The endothelial glycocalyx is a primary target during the early phase of sepsis. We previously reported a newly developed recombinant non-fucosylated antithrombin has protective effects in vitro. We further evaluated the effects of this recombinant antithrombin on the glycocalyx dama...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Iba, Toshiaki, Levy, Jerrold H., Aihara, Koichiro, Kadota, Katsuhiko, Tanaka, Hiroshi, Sato, Koichi, Nagaoka, Isao
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795760/
https://ncbi.nlm.nih.gov/pubmed/33375342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010176
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