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The Interactions of Nintedanib and Oral Anticoagulants—Molecular Mechanisms and Clinical Implications

Nintedanib is a synthetic orally active tyrosine kinase inhibitor, whose main action is to inhibit the receptors of the platelet-derived growth factor, fibroblast growth factor and vascular endothelial growth factor families. The drug also affects other kinases, including Src, Flt-3, LCK, LYN. Ninte...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Grześk, Grzegorz, Woźniak-Wiśniewska, Anita, Błażejewski, Jan, Górny, Bartosz, Wołowiec, Łukasz, Rogowicz, Daniel, Nowaczyk, Alicja
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795697/
https://ncbi.nlm.nih.gov/pubmed/33396592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010282
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