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Plasticity of Intestinal Epithelium: Stem Cell Niches and Regulatory Signals

The discovery of Lgr5+ intestinal stem cells (ISCs) triggered a breakthrough in the field of ISC research. Lgr5+ ISCs maintain the homeostasis of the intestinal epithelium in the steady state, while these cells are susceptible to epithelial damage induced by chemicals, pathogens, or irradiation. Dur...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Autores principales: Kurokawa, Ken, Hayakawa, Yoku, Koike, Kazuhiko
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7795504/
https://ncbi.nlm.nih.gov/pubmed/33396437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010357
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