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Alterations in the Genomic Distribution of 5hmC in In Vivo Aged Human Skin Fibroblasts
5-Hydroxymethylcytosine (5hmC) is a functionally active epigenetic modification. We analyzed whether changes in DNA 5-hydroxymethylation are an element of age-related epigenetic drift. We tested primary fibroblast cultures originating from individuals aged 22–35 years and 74–94 years. Global quantit...
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| Publicado no: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7794952/ https://ncbi.nlm.nih.gov/pubmed/33374812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010078 |
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