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Therapeutic Potential of the Molecular Chaperone and Matrix Metalloproteinase Inhibitor Clusterin for Dry Eye

Evidence is presented herein supporting the potential of the natural homeostatic glycoprotein CLU (clusterin) as a novel therapeutic for the treatment of dry eye. This idea began with the demonstration that matrix metalloproteinase MMP9 is required for damage to the ocular surface in mouse dry eye....

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Vydáno v:Int J Mol Sci
Hlavní autoři: Fini, M. Elizabeth, Jeong, Shinwu, Wilson, Mark R.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794831/
https://ncbi.nlm.nih.gov/pubmed/33374364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010116
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