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Kaempferol Inhibits Zearalenone-Induced Oxidative Stress and Apoptosis via the PI3K/Akt-Mediated Nrf2 Signaling Pathway: In Vitro and In Vivo Studies

In this study, kaempferol (KFL) shows hepatoprotective activity against zearalenone (ZEA)-induced oxidative stress and its underlying mechanisms in in vitro and in vivo models were investigated. Oxidative stress plays a critical role in the pathophysiology of various hepatic ailments and is normally...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Rajendran, Peramaiyan, Ammar, Rebai Ben, Al-Saeedi, Fatma J., Mohamed, Maged E., ElNaggar, Medhat A., Al-Ramadan, Saeed Y., Bekhet, Gamal M., Soliman, Ahmed M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794799/
https://ncbi.nlm.nih.gov/pubmed/33379332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010217
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