Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial

BACKGROUND: Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD substrain vaccine. We assessed the immunogenicity and safety of one-fifth fractional dose compared with standard d...

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Publicado en:Lancet
Autores principales: Juan-Giner, Aitana, Kimathi, Derick, Grantz, Kyra H, Hamaluba, Mainga, Kazooba, Patrick, Njuguna, Patricia, Fall, Gamou, Dia, Moussa, Bob, Ndeye S, Monath, Thomas P, Barrett, Alan D, Hombach, Joachim, Mulogo, Edgar M, Ampeire, Immaculate, Karanja, Henry K, Nyehangane, Dan, Mwanga-Amumpaire, Juliet, Cummings, Derek A T, Bejon, Philip, Warimwe, George M, Grais, Rebecca F
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794660/
https://ncbi.nlm.nih.gov/pubmed/33422245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(20)32520-4
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