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False negative rate of COVID-19 PCR testing: a discordant testing analysis

BACKGROUND: COVID-19 is diagnosed via detection of SARS-CoV-2 RNA using real time reverse-transcriptase polymerase chain reaction (rtRT-PCR). Performance of many SARS-CoV-2 rtRT-PCR assays is not entirely known due to the lack of a gold standard. We sought to evaluate the false negative rate (FNR) a...

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Bibliografiske detaljer
Udgivet i:Virol J
Main Authors: Kanji, Jamil N., Zelyas, Nathan, MacDonald, Clayton, Pabbaraju, Kanti, Khan, Muhammad Naeem, Prasad, Abhaya, Hu, Jia, Diggle, Mathew, Berenger, Byron M., Tipples, Graham
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794619/
https://ncbi.nlm.nih.gov/pubmed/33422083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-021-01489-0
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