A novel role of MNT as a negative regulator of REL and the NF-κB pathway

MNT, a transcription factor of the MXD family, is an important modulator of the oncoprotein MYC. Both MNT and MYC are basic-helix–loop–helix proteins that heterodimerize with MAX in a mutually exclusive manner, and bind to E-boxes within regulatory regions of their target genes. While MYC generally...

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Udgivet i:Oncogenesis
Main Authors: Liaño-Pons, Judit, Lafita-Navarro, M. Carmen, García-Gaipo, Lorena, Colomer, Carlota, Rodríguez, Javier, von Kriegsheim, Alex, Hurlin, Peter J., Ourique, Fabiana, Delgado, M. Dolores, Bigas, Anna, Espinosa, Lluis, León, Javier
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794610/
https://ncbi.nlm.nih.gov/pubmed/33419981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-020-00298-4
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