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The severity of the pathogen-induced acute sickness response is affected by polymorphisms in genes of the NLRP3 inflammasome pathway

The acute sickness response (ASR) is a stereotyped set of symptoms including fatigue, pain, and disturbed mood, which are present in most acute infections. The immunological mechanisms of the ASR are conserved, with variations in severity determined partly by the pathogen, but also by polymorphisms...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Valencia, Braulio M., Cvejic, Erin, Vollmer-Conna, Ute, Hickie, Ian B., Wakefield, Denis, Li, Hui, Pedergnana, Vincent, Rodrigo, Chaturaka, Lloyd, Andrew R.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794598/
https://ncbi.nlm.nih.gov/pubmed/33434563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2021.01.005
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