An experimental pig model with outer retinal degeneration induced by temporary intravitreal loading of N-methyl-N-nitrosourea during vitrectomy

We aimed to develop an outer retinal degeneration pig model induced by temporary intravitreal loading of N-methyl-N-nitrosourea (MNU) during vitrectomy. In a preliminary experiment involving 5 mini-pig cases to determine the appropriate concentration of MNU, the vitreous cavity of each eye was fille...

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Gepubliceerd in:Sci Rep
Hoofdauteurs: Choi, Kwang-Eon, Anh, Vu Thi Que, Kim, Jee Taek, Yun, Cheolmin, Cha, Seongkwang, Ahn, Jungryul, Goo, Yong Sook, Kim, Seong-Woo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794530/
https://ncbi.nlm.nih.gov/pubmed/33420119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79437-1
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