Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis

Neutrophils form neutrophil extracellular traps (NETs), which are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Recent reports suggest that platelets stimulated via toll-like receptor (TLR) pathways can induce NETs formation. However, the mechanism underlying the involvement of p...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Matsumoto, Kotaro, Yasuoka, Hidekata, Yoshimoto, Keiko, Suzuki, Katsuya, Takeuchi, Tsutomu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794527/
https://ncbi.nlm.nih.gov/pubmed/33420306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80685-4
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