Metabolic changes and anti-tumor effects of a ketogenic diet combined with anti-angiogenic therapy in a glioblastoma mouse model

The ketogenic diet (KD) is a high fat and low carbohydrate diet that produces ketone bodies through imitation of starvation. The combination of KD and Bevacizumab (Bev), a VEGF inhibitor, is considered to further reduce the supply of glucose to the tumor. The metabolite changes in U87 glioblastoma m...

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Publicado en:Sci Rep
Autores principales: Maeyama, Masahiro, Tanaka, Kazuhiro, Nishihara, Masamitsu, Irino, Yasuhiro, Shinohara, Masakazu, Nagashima, Hiroaki, Tanaka, Hirotomo, Nakamizo, Satoshi, Hashiguchi, Mitsuru, Fujita, Yuichi, Kohta, Masaaki, Kohmura, Eiji, Sasayama, Takashi
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2021
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794443/
https://ncbi.nlm.nih.gov/pubmed/33420169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79465-x
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