Spatiotemporal analysis of soluble aggregates and autophagy markers in the R6/2 mouse model

Maintenance of cellular proteostasis is vital for post-mitotic cells like neurons to sustain normal physiological function and homeostasis, defects in which are established hallmarks of several age-related conditions like AD, PD, HD, and ALS. The Spatio-temporal accumulation of aggregated proteins i...

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Udgivet i:Sci Rep
Main Authors: Kumar, M. J. Vijay, Shah, Devanshi, Giridharan, Mridhula, Yadav, Niraj, Manjithaya, Ravi, Clement, James P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794371/
https://ncbi.nlm.nih.gov/pubmed/33420088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78850-w
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