The spatial RNA integrity number assay for in situ evaluation of transcriptome quality

The RNA integrity number (RIN) is a frequently used quality metric to assess the completeness of rRNA, as a proxy for the corresponding mRNA in a tissue. Current methods operate at bulk resolution and provide a single average estimate for the whole sample. Spatial transcriptomics technologies have e...

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Publicado no:Commun Biol
Main Authors: Kvastad, Linda, Carlberg, Konstantin, Larsson, Ludvig, Villacampa, Eva Gracia, Stuckey, Alexander, Stenbeck, Linnea, Mollbrink, Annelie, Zamboni, Margherita, Magnusson, Jens Peter, Basmaci, Elisa, Shamikh, Alia, Prochazka, Gabriela, Schaupp, Anna-Lena, Borg, Åke, Fugger, Lars, Nistér, Monica, Lundeberg, Joakim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794352/
https://ncbi.nlm.nih.gov/pubmed/33420318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01573-1
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