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Host mitochondrial transcriptome response to SARS-CoV-2 in multiple cell models and clinical samples

SARS-CoV-2 induces a muted innate immune response compared to other respiratory viruses. Mitochondrial dynamics might partially mediate this effect of SARS-CoV-2 on innate immunity. Polypeptides encoded by open reading frames of SARS-CoV and SARS-CoV-2 have been shown to localize to mitochondria and...

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Publicat a:Sci Rep
Autors principals: Miller, Brendan, Silverstein, Ana, Flores, Melanie, Cao, Kevin, Kumagai, Hiroshi, Mehta, Hemal H., Yen, Kelvin, Kim, Su- Jeong, Cohen, Pinchas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794290/
https://ncbi.nlm.nih.gov/pubmed/33420163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-79552-z
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