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Investigating the influence of physiologically relevant hydrostatic pressure on CHO cell batch culture

Chinese hamster ovary (CHO) cells have been the most commonly used mammalian host for large-scale commercial production of therapeutic proteins, such as monoclonal antibodies. Enhancement of productivity of these CHO cells is one of the top priorities in the biopharmaceutical industry to reduce manu...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shang, Menglin, Kwon, Taehong, Hamel, Jean-Francois P., Lim, Chwee Teck, Khoo, Bee Luan, Han, Jongyoon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794228/
https://ncbi.nlm.nih.gov/pubmed/33420324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-80576-8
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